Torulene dioxygenase

Torulene dioxygenase
Identifiers
EC number 1.13.11.59
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Torulene dioxygenase (EC 1.13.11.59, CAO-2, CarT) is an enzyme with systematic name torulene:oxygen oxidoreductase.[1][2][3] This enzyme catalyses the following chemical reaction

torulene + O2 4'-apo-beta,psi-caroten-4'-al + 3-methylbut-2-enal

It is assumed that 3-methylbut-2-enal is formed.

References

  1. Prado-Cabrero, A.; Estrada, A.F.; Al-Babili, S.; Avalos, J. (2007). "Identification and biochemical characterization of a novel carotenoid oxygenase: elucidation of the cleavage step in the Fusarium carotenoid pathway". Mol. Microbiol. 64 (2): 448–460. doi:10.1111/j.1365-2958.2007.05665.x. PMID 17493127.
  2. Saelices, L.; Youssar, L.; Holdermann, I.; Al-Babili, S.; Avalos, J. (2007). "Identification of the gene responsible for torulene cleavage in the Neurospora carotenoid pathway". Mol. Genet. Genomics. 278 (5): 527–537. doi:10.1007/s00438-007-0269-2. PMID 17610084.
  3. Estrada, A.F.; Maier, D.; Scherzinger, D.; Avalos, J.; Al-Babili, S. (2008). "Novel apocarotenoid intermediates in Neurospora crassa mutants imply a new biosynthetic reaction sequence leading to neurosporaxanthin formation". Fungal Genet. Biol. 45 (11): 1497–1505. doi:10.1016/j.fgb.2008.09.001. PMID 18812228.
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