Salicylate decarboxylase

Salicylate decarboxylase
Identifiers
EC number 4.1.1.91
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Salicylate decarboxylase (EC 4.1.1.91, salicylic acid decarboxylase, Scd) is an enzyme with systematic name salicylate carboxy-lyase.[1] This enzyme catalyses the following chemical reaction

salicylate phenol + CO2

In the reverse direction the enzyme catalyses the regioselective carboxylation of phenol into salicylate.

References

  1. Kirimura, K.; Gunji, H.; Wakayama, R.; Hattori, T.; Ishii, Y. (2010). "Enzymatic Kolbe-Schmitt reaction to form salicylic acid from phenol: enzymatic characterization and gene identification of a novel enzyme, Trichosporon moniliiforme salicylic acid decarboxylase". Biochem. Biophys. Res. Commun. 394: 279–284. doi:10.1016/j.bbrc.2010.02.154. PMID 20188702.
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