Ribosylnicotinamide kinase

ribosylnicotinamide kinase
Identifiers
EC number 2.7.1.22
CAS number 9030-61-9
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a ribosylnicotinamide kinase (EC 2.7.1.22) is an enzyme that catalyzes the chemical reaction

ATP + N-ribosylnicotinamide ADP + nicotinamide ribonucleotide

Thus, the two substrates of this enzyme are ATP and N-ribosylnicotinamide, whereas its two products are ADP and nicotinamide ribonucleotide.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:N-ribosylnicotinamide 5'-phosphotransferase. This enzyme is also called ribosylnicotinamide kinase (phosphorylating). This enzyme participates in nicotinate and nicotinamide metabolism.

Health

Studies show potential for obesity treatment and for longer healthier life. Ribosylnicotinamide kinasee seems to activate similar genes that Resveratrol does.

Food

The enzyme can be found in milk and beer. Since the molecules are difficult to detect, it is expected that there is a lot more food products containing ribosylnicotinamide kinase.

References


    This article is issued from Wikipedia - version of the 8/10/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.