Pseudobaptigenin synthase

Pseudobaptigenin synthase
Identifiers
EC number 1.14.21.8
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Pseudobaptigenin synthase (EC 1.14.21.8) is an enzyme with systematic name calycosin,NADPH:oxygen oxidoreductase (methylenedioxy-bridge-forming).[1] This enzyme catalyses the following chemical reaction

(1) calycosin + NADPH + H+ + O2 pseudobaptigenin + NADP+ + 2 H2O
(2) pratensein + NADPH + H+ + O2 5-hydroxypseudobaptigenin + NADP+ + 2 H2O

Pseudobaptigenin synthase is a heme-thiolate enzyme (P450) that catalyses a step in the biosynthesis of (-)-maackiain.

References

  1. Clemens S.; Barz W. (1996). "Cytochrome P450-dependent methylenedioxy bridge formation in Cicer arietinum". Phytochemistry. 41: 457–460. doi:10.1016/0031-9422(95)00618-4.
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