Pseudaminic acid synthase
| Pseudaminic acid synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.5.1.97 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Pseudaminic acid synthase (EC 2.5.1.97, PseI, NeuB3) is an enzyme with systematic name phosphoenolpyruvate:2,4-bis(acetylamino)-2,4,6-trideoxy-beta-L-altropyranose transferase (phosphate-hydrolysing, 2,7-acetylamino-transferring, 2-carboxy-2-oxoethyl-forming).[1] This enzyme catalyses the following chemical reaction
- phosphoenolpyruvate + 2,4-bis(acetylamino)-2,4,6-trideoxy-beta-L-altropyranose + H2O 5,7-bis(acetylamino)-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-2-nonulopyranosonic acid + phosphate
The enzyme requires a divalent metal ion, preferably Mn2+ and Co2+.
References
- ↑ Chou, W.K.; Dick, S.; Wakarchuk, W.W.; Tanner, M.E. (2005). "Identification and characterization of NeuB3 from Campylobacter jejuni as a pseudaminic acid synthase". J. Biol. Chem. 280 (43): 35922–35928. doi:10.1074/jbc.M507483200. PMID 16120604.
External links
- Pseudaminic acid synthase at the US National Library of Medicine Medical Subject Headings (MeSH)
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