Pantoate kinase

Pantoate kinase
Identifiers
EC number 2.7.1.169
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Pantoate kinase (EC 2.7.1.169, PoK, TK2141 protein) is an enzyme with systematic name ATP:(R)-pantoate 4-phosphotransferase.[1] This enzyme catalyses the following chemical reaction

ATP + (R)-pantoate ADP + (R)-4-phosphopantoate

The conversion of (R)-pantoate to (R)-4'-phosphopantothenate is done during biosynthesis of 4'-phosphopantetheine,.

References

  1. Yokooji, Y.; Tomita, H.; Atomi, H.; Imanaka, T. (2009). "Pantoate kinase and phosphopantothenate synthetase, two novel enzymes necessary for CoA biosynthesis in the Archaea". J. Biol. Chem. 284: 28137–28145. doi:10.1074/jbc.m109.009696. PMID 19666462.
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