Nitrate reductase (NADPH)

Nitrate reductase (NADPH)
Identifiers
EC number 1.7.1.3
CAS number 9029-28-1
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Nitrate reductase (NADPH) (EC 1.7.1.3, assimilatory nitrate reductase, assimilatory reduced nicotinamide adenine dinucleotide phosphate-nitrate reductase, NADPH-nitrate reductase, assimilatory NADPH-nitrate reductase, triphosphopyridine nucleotide-nitrate reductase, NADPH:nitrate reductase, nitrate reductase (NADPH2), NADPH2:nitrate oxidoreductase) is an enzyme with systematic name nitrite:NADP+ oxidoreductase.[1][2][3][4] This enzyme catalises the following chemical reaction

nitrite + NADP+ + H2O nitrate + NADPH + H+

Nitrate reductase is an iron-sulfur molybdenum flavoprotein.

References

  1. Nason, A. (1963). "Nitrate reductases". In Boyer, P.D.; Lardy, H.; Myrbäck, K. The Enzymes. 7 (2nd ed.). New York: Academic Press. pp. 587–607.
  2. Nason, A.; Evans, H.J. (1953). "Triphosphopyridine nucleotide-nitrate reductase in Neurospora". J. Biol. Chem. 202: 655–673. PMID 13061490.
  3. Nicholas, D.J.D.; Nason, A. (1954). "Molybdenum and nitrate reductase. II. Molybdenum as a constituent of nitrate reductase". J. Biol. Chem. 207: 353–360. PMID 13152110.
  4. Berks, B.C.; Ferguson, S.J.; Moir, J.W.; Richardson, D.J. (1995). "Enzymes and associated electron transport systems that catalyse the respiratory reduction of nitrogen oxides and oxyanions". Biochim. Biophys. Acta. 1232: 97–173. doi:10.1016/0005-2728(95)00092-5. PMID 8534676.
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