Geranyl-pyrophosphate—olivetolic acid geranyltransferase

Geranyl-pyrophosphate—olivetolic acid geranyltransferase
Identifiers
EC number 2.5.1.102
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Geranyl-pyrophosphate—olivetolic acid geranyltransferase (EC 2.5.1.102, GOT) is an enzyme with systematic name geranyl-diphosphate:olivetolate geranyltransferase.[1] This enzyme catalyses the following chemical reaction

geranyl diphosphate + 2,4-dihydroxy-6-pentylbenzoate diphosphate + cannabigerolate

Part of the cannabinoids biosynthetic pathway of the plant Cannabis sativa.

References

  1. Fellermeier, M.; Zenk, M.H. (1998). "Prenylation of olivetolate by a hemp transferase yields cannabigerolic acid, the precursor of tetrahydrocannabinol". FEBS Lett. 427: 283–285. doi:10.1016/S0014-5793(98)00450-5. PMID 9607329.
This article is issued from Wikipedia - version of the 5/19/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.