Gamma-curcumene synthase

Gamma-curcumene synthase
Identifiers
EC number 4.2.3.94
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Gamma-curcumene synthase (EC 4.2.3.94, PatTpsA (gene)) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, gamma-curcumene-forming).[1] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate gamma-curcumene + diphosphate

This enzyme is one of five sesquiterpenoid synthases in Pogostemon cablin (patchouli).

References

  1. Deguerry, F.; Pastore, L.; Wu, S.; Clark, A.; Chappell, J.; Schalk, M. (2006). "The diverse sesquiterpene profile of patchouli, Pogostemon cablin, is correlated with a limited number of sesquiterpene synthases". Arch. Biochem. Biophys. 454: 123–136. doi:10.1016/j.abb.2006.08.006. PMID 16970904.
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