Fumigaclavine B O-acetyltransferase

Fumigaclavine B O-acetyltransferase
Identifiers
EC number 2.3.1.205
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Fumigaclavine B O-acetyltransferase (EC 2.3.1.205, FgaAT) is an enzyme with systematic name acetyl-CoA:fumigaclavine B O-acetyltransferase.[1] This enzyme catalyses the following chemical reaction

acetyl-CoA + fumigaclavine B CoA + fumigaclavine A

The enzyme participates in the biosynthesis of fumigaclavine C, an ergot alkaloid.

References

  1. Liu, X.; Wang, L.; Steffan, N.; Yin, W.B.; Li, S.M. (2009). "Ergot alkaloid biosynthesis in Aspergillus fumigatus: FgaAT catalyses the acetylation of fumigaclavine B". ChemBioChem. 10: 2325–2328. doi:10.1002/cbic.200900395. PMID 19672909.
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