Dipeptidyl-peptidase III

Dipeptidyl-peptidase III
Identifiers
EC number 3.4.14.4
CAS number 77464-87-0
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Dipeptidyl-peptidase III (EC 3.4.14.4, dipeptidyl aminopeptidase III, dipeptidyl arylamidase III, enkephalinase B, red cell angiotensinase) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction

Release of an N-terminal dipeptide from a peptide comprising four or more residues, with broad specificity. Also acts on dipeptidyl 2-naphthylamides.

This cytosolic peptidase that is active at neutral pH.

References

  1. McDonald, J.K.; Rawlings, N.D.; Woessner, J.F. (1998). "Dipeptidyl-peptidase III". In Barrett, A.J. Handbook of Proteolytic Enzymes. London: Handbook of Proteolytic Enzymes. pp. 536–538.
  2. Fukasawa, K.; Fukasawa, K.M.; Iwamoto, H.; Hirose, J.; Harada, M. (1999). "The HELLGH motif of rat liver dipeptidyl peptidase III is involved in zinc coordination and the catalytic activity of the enzyme". Biochemistry. 38: 8299–8303. doi:10.1021/bi9904959. PMID 10387075.

External links

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