D-lactate dehydratase

D-lactate dehydratase
Identifiers
EC number 4.2.1.130
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

D-lactate dehydratase (EC 4.2.1.130, glyoxylase III) is an enzyme with systematic name (R)-lactate hydro-lyase.[1][2] This enzyme catalyses the following chemical reaction

(R)-lactate methylglyoxal + H2O

The enzyme converts methylglyoxal to D-lactate.

References

  1. Misra, K.; Banerjee, A.B.; Ray, S.; Ray, M. (1995). "Glyoxalase III from Escherichia coli: a single novel enzyme for the conversion of methylglyoxal into D-lactate without reduced glutathione". Biochem. J. 305: 999–1003. PMID 7848303.
  2. Subedi, K.P.; Choi, D.; Kim, I.; Min, B.; Park, C. (2011). "Hsp31 of Escherichia coli K-12 is glyoxalase III". Mol. Microbiol. 81: 926–936. doi:10.1111/j.1365-2958.2011.07736.x. PMID 21696459.

External links

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