D-arabitol-phosphate dehydrogenase

D-arabitol-phosphate dehydrogenase
Identifiers
EC number 1.1.1.301
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

D-arabitol-phosphate dehydrogenase (EC 1.1.1.301, APDH, D-arabitol 1-phosphate dehydrogenase, D-arabitol 5-phosphate dehydrogenase) is an enzyme with systematic name D-arabitol-phosphate:NAD+ oxidoreductase.[1] This enzyme catalyses the following chemical reaction

D-arabitol 1-phosphate + NAD+ D-xylulose 5-phosphate + NADH + H+

This enzyme participates in arabitol catabolism. The enzyme also converts D-arabitol 5-phosphate to D-ribulose 5-phosphate at a lower rate.

References

  1. Povelainen, M.; Eneyskaya, E. V.; Kulminskaya, A. A.; Ivanen, D. R.; Kalkkinen, N.; Neustroev, K. N.; Miasnikov, A. N. (2003). "Biochemical and genetic characterization of a novel enzyme of pentitol metabolism: D-arabitol-phosphate dehydrogenase". Biochem. J. 371 (Pt 1): 191–197. doi:10.1042/BJ20021096. PMC 1223252Freely accessible. PMID 12467497.

External links

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