D-arabinitol dehydrogenase (NADP+)

D-arabinitol dehydrogenase (NADP+)
Identifiers
EC number 1.1.1.287
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

D-arabinitol dehydrogenase (NADP+) (EC 1.1.1.287, NADP+-dependent D-arabitol dehydrogenase, ARD1p, D-arabitol dehydrogenase 1) is an enzyme with systematic name D-arabinitol:NADP+ oxidoreductase.[1] This enzyme catalyses the following chemical reaction

(1) D-arabinitol + NADP+ D-xylulose + NADPH + H+
(2) D-arabinitol + NADP+ D-ribulose + NADPH + H+

The enzyme present in the fungus Uromyces fabae can make use D-arabinitol and D-mannitol in the forward direction, and D-xylulose, D-ribulose and D-fructose in the reverse direction.

References

  1. Link, T.; Lohaus, G.; Heiser, I.; Mendgen, K.; Hahn, M.; Voegele, R.T. (2005). "Characterization of a novel NADP+-dependent D-arabitol dehydrogenase from the plant pathogen Uromyces fabae". Biochem. J. 389 (Pt 2): 289–295. doi:10.1042/BJ20050301. PMC 1175105Freely accessible. PMID 15796718.

External links

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