Atrolysin F

Atrolysin F
Identifiers
EC number 3.4.24.45
CAS number 172306-52-4
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Atrolysin F (EC 3.4.24.45, Crotalus atrox metalloendopeptidase, hemorrhagic toxin f, Crotalus atrox metalloendopeptidase f) is an enzyme.[1] This enzyme catalyses the following chemical reaction

Cleavage of Val2-Asn, Gln4-His, Leu6-Cys, His10-Leu, Ala14-Leu and Tyr16-Leu bonds in insulin B chain

This endopeptidase is present in the venom of the western diamondback rattlesnake (Crotalus atrox).

References

  1. Nikai, T.; Mori, N.; Kishida, M.; Sugihara, H.; Tu, A.T. (1984). "Isolation and biochemical characterization of hemorrhagic toxin f from the venom of Crotalus atrox (western diamondback rattlesnake)". Arch. Biochem. Biophys. 231: 309–319. doi:10.1016/0003-9861(84)90393-x. PMID 6375570.

External links

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