APOA1BP

apolipoprotein A-I-binding protein
Identifiers
Symbol APOA1BP
Entrez 128240
HUGO 18453
OMIM 608862
RefSeq NM_144772
UniProt Q8NCW5
Other data
Locus Chr. 1 q21

Apolipoprotein A-I-binding protein also known as APOA1BP is a protein that in humans is encoded by the APOA1BP gene.[1]

Function

APOA1BP binds to APOA1, APOA2, and high-density lipoprotein (HDL).[1] In addition, APOA1BP appears to play a role in sperm capacitation.[2]

References

  1. 1 2 Ritter M, Buechler C, Boettcher A, Barlage S, Schmitz-Madry A, Orsó E, Bared SM, Schmiedeknecht G, Baehr CH, Fricker G, Schmitz G (May 2002). "Cloning and characterization of a novel apolipoprotein A-I binding protein, AI-BP, secreted by cells of the kidney proximal tubules in response to HDL or ApoA-I". Genomics. 79 (5): 693–702. doi:10.1006/geno.2002.6761. PMID 11991719.
  2. Jha KN, Shumilin IA, Digilio LC, Chertihin O, Zheng H, Schmitz G, Visconti PE, Flickinger CJ, Minor W, Herr JC (May 2008). "Biochemical and Structural Characterization of Apolipoprotein A-I Binding Protein, a Novel Phosphoprotein with a Potential Role in Sperm Capacitation". Endocrinology. 149 (5): 2108–20. doi:10.1210/en.2007-0582. PMC 2329272Freely accessible. PMID 18202122.
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