7-carboxy-7-deazaguanine synthase
| 7-carboxy-7-deazaguanine synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 4.3.99.3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
7-carboxy-7-deazaguanine synthase (EC 4.3.99.3, 7-carboxy-7-carbaguanine synthase, queE (gene)) is an enzyme with systematic name 6-carboxy-5,6,7,8-tetrahydropterin ammonia-lyase.[1] This enzyme catalyses the following chemical reaction
- 6-carboxy-5,6,7,8-tetrahydropterin 7-carboxy-7-carbaguanine + NH3
The enzyme is a member of the superfamily of S-adenosyl-L-methionine-dependent radical enzymes.
References
- ↑ McCarty, R.M.; Somogyi, A.; Lin, G.; Jacobsen, N.E.; Bandarian, V. (2009). "The deazapurine biosynthetic pathway revealed: in vitro enzymatic synthesis of preQ0 from guanosine 5′-triphosphate in four steps". Biochemistry. 48: 3847–3852. doi:10.1021/bi900400e. PMID 19354300.
External links
- 7-carboxy-7-deazaguanine synthase at the US National Library of Medicine Medical Subject Headings (MeSH)
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