3-dehydroshikimate dehydratase

3-dehydroshikimate dehydratase
Identifiers
EC number 4.2.1.118
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

3-dehydroshikimate dehydratase (EC 4.2.1.118) is an enzyme with systematic name 3-dehydroshikimate hydro-lyase.[1][2] This enzyme catalyses the following chemical reaction

3-dehydro-shikimate protocatechuate + H2O

This enzyme catalyses an early step in the biosynthesis of petrobactin.

References

  1. Fox, D.T.; Hotta, K.; Kim, C.Y.; Koppisch, A.T. (2008). "The missing link in petrobactin biosynthesis: asbF encodes a (-)-3-dehydroshikimate dehydratase". Biochemistry. 47: 12251–12253. doi:10.1021/bi801876q. PMID 18975921.
  2. Pfleger, B.F.; Kim, Y.; Nusca, T.D.; Maltseva, N.; Lee, J.Y.; Rath, C.M.; Scaglione, J.B.; Janes, B.K.; Anderson, E.C.; Bergman, N.H.; Hanna, P.C.; Joachimiak, A.; Sherman, D.H. (2008). "Structural and functional analysis of AsbF: origin of the stealth 3,4-dihydroxybenzoic acid subunit for petrobactin biosynthesis". Proc. Natl. Acad. Sci. USA. 105: 17133–17138. doi:10.1073/pnas.0808118105. PMID 18955706.

External links

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